Abstract | OBJECTIVE: METHODS: We retrospectively analyzed the records of 361 stroke-free subjects who consecutively visited a general health promotion center. Included subjects had serum calcium, phosphate, and albumin drawn and underwent brain magnetic resonance angiography. The basilar, middle cerebral, intracranial internal carotid, and intracranial vertebral arteries were evaluated. Serum calcium concentration was corrected for serum albumin concentration. RESULTS: Mean ± SD values were 52 ± 10 years for age, 2.35 ± 0.09 mmol/l for uncorrected serum calcium concentration, 2.24 ± 0.08 mmol/l for corrected serum calcium concentration, and 1.19 ± 0.18 mmol/l for serum phosphate concentration. Seventy-four subjects (21%) had intracranial atherosclerosis. Subjects in the upper three quartiles of corrected serum calcium concentration had a significantly greater risk for intracranial atherosclerosis compared with the lowest quartile with the odds ratios of 3.50 (95% confidence interval 1.50-8.15), 3.11 (95% confidence interval 1.26-7.69), and 3.77 (95% confidence interval 1.58-9.03), respectively. However, serum phosphate and uncorrected serum calcium concentrations were not associated with intracranial atherosclerosis. CONCLUSION:
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Authors | K Kang |
Journal | Atherosclerosis
(Atherosclerosis)
Vol. 232
Issue 1
Pg. 249-53
(Jan 2014)
ISSN: 1879-1484 [Electronic] Ireland |
PMID | 24401247
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2013 Elsevier Ireland Ltd. All rights reserved. |
Chemical References |
- Albumins
- Phosphates
- Calcium
|
Topics |
- Adult
- Aged
- Albumins
(chemistry)
- Brain
(pathology)
- Calcium
(blood)
- Female
- Humans
- Intracranial Arteriosclerosis
(blood)
- Magnetic Resonance Angiography
- Male
- Middle Aged
- Odds Ratio
- Phosphates
(blood)
- Republic of Korea
- Retrospective Studies
- Risk Factors
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