Abstract | BACKGROUND: Compliance is often partial with oral antipsychotics and underestimated for patients with serious mental illness. Despite their demonstrated advantages in terms of relapse prevention, depot formulations are still poorly used in routine. As part of a process to improve the quality of care, French Association for Biological Psychiatry and Neuropsychopharmacology (AFPBN) Task Force elaborated a Formal Consensus for the prescription of depot antipsychotics in clinical practice. METHODS: RESULTS: LAI formulations should be systematically proposed to any patients for whom maintenance antipsychotic treatment is indicated. LAI antipsychotics can be used preferentially for non-compliant patients with frequent relapses or aggressive behaviors. CONCLUSION: A specific information concerning the advantages and inconveniences of the LAI formulations, in the framework of shared-decision making must be delivered to each patient. Recommendations for switching from one oral/LAI form to another LAI and for using LAI antipsychotics in specific populations (pregnant women, elderly patients, subjects in a precarious situation, and subjects having to be treated in a prison establishment) are also proposed.
|
Authors | L Samalin, M Abbar, P Courtet, S Guillaume, S Lancrenon, P-M Llorca |
Journal | L'Encephale
(Encephale)
Vol. 39 Suppl 4
Pg. 189-203
(Dec 2013)
ISSN: 0013-7006 [Print] France |
Vernacular Title | Recommandations Formalisées d'Experts de l'AFPBN : prescription des neuroleptiques et antipsychotiques d'action prolongée. |
PMID | 24373464
(Publication Type: Consensus Development Conference, English Abstract, Journal Article, Practice Guideline)
|
Copyright | Copyright © 2013 L’Encéphale. Published by Elsevier Masson SAS.. All rights reserved. |
Chemical References |
- Anticonvulsants
- Antipsychotic Agents
- Delayed-Action Preparations
|
Topics |
- Administration, Oral
- Adult
- Anticonvulsants
(adverse effects, therapeutic use)
- Antipsychotic Agents
(administration & dosage, adverse effects, therapeutic use)
- Bipolar Disorder
(diagnosis, drug therapy, psychology)
- Delayed-Action Preparations
- Drug Therapy, Combination
- Female
- France
- Humans
- Injections, Intramuscular
- Male
- Medication Adherence
- Middle Aged
- Psychotic Disorders
(diagnosis, drug therapy, psychology)
- Quality Improvement
- Schizophrenia
(diagnosis, drug therapy)
- Schizophrenia, Paranoid
(diagnosis, drug therapy, psychology)
- Schizophrenic Psychology
- Secondary Prevention
- Societies, Medical
|