Conjunctival
mucoepidermoid carcinoma is a very rare but highly aggressive
conjunctival neoplasm with 42 previously reported cases. We report the case of a 56-year-old male with a left ocular surface squamous
neoplasm, which was subsequently treated with excision and autoconjunctival graft. Histopathology of the operative specimen reported a low-grade conjunctival
mucoepidermoid carcinoma, and the patient was then treated with an adjunctive course of
mitomycin C. On review 10 months after lesion excision, there was no recurrence, and the patient was otherwise well. Due to its rare incidence, difficult clinical diagnosis, and accompanying poor prognosis, conjunctival
mucoepidermoid carcinoma should always be considered in the differential diagnosis of
conjunctival neoplasms, and full histopathologic examination, including
mucin-staining techniques, of all suspicious conjunctival biopsies should occur.