[The use of autoplasma rich in platelet growth factors (APRPGF) on results of treatment of patients with pilonidal sinus abscess].

Abstract

The subject of the study was to assess the influence of local application of autoplasma rich in platelet growth factors (APRPGF) on results of treatment of patients with pilonidal sinus abscess. Results of treatment of 248 patients with pilonidal sinus abscess are presented. Middle age was 24.3±9.2 years. All patients were operated on in one stage with a small excision of a skin lap in the pilonidal sinus zone with an open wound care in the postoperative period. All patients were divided in two groups. Patients of the first group received the traditional postoperative treatment. The APRPGF was additionally used for the patients from the second group (the drug was injected into walls and bottom of the wound and imposed on the wound on a medicine carrier with platelet growth factor). It was shown that local application of APRPGF promoted the activation of reparation in a wound and reduction of the healing time (the 1st group - 40.1±5 days, the 2nd group - 25.7±3 days).

• Authors: E E Achkasov, A A Ul'ianov, E N Bezuglov
• Journal: Khirurgiia (Khirurgiia (Mosk)) Issue 12 Pg. 43-7 ( 2013) ISSN: 0023-1207 [Print] Russia (Federation)
• PMID: 24362291 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Intercellular Signaling Peptides and Proteins

Topics

• Abscess (surgery)
• Adult
• Female
• Follow-Up Studies
• Humans
• Injections
• Intercellular Signaling Peptides and Proteins
• Male
• Pilonidal Sinus (surgery)
• Platelet-Rich Plasma
• Retrospective Studies
• Surgical Flaps
• Treatment Outcome
• Wound Healing
• Young Adult