Abstract | OBJECTIVES: METHODS: We present a patient from our institution with thyroid storm and FHF. A literature review was performed to analyze the outcomes of the 6 additional cases of concomitant thyroid storm and FHF. RESULTS: Our patient underwent thyroidectomy followed by OLT. Her serum levels of thyroid-stimulating hormone, triiodothyronine, thyroxine, and transaminase normalized, and she was ready for discharge within 10 days of surgery. She has survived without complication. There is a 40% mortality rate for the reported patients treated medically with these conditions. Of the 7 total cases of reported FHF and thyroid storm, 2 patients died. Only 2 of the 7 patients underwent thyroidectomy and OLT--both at our institution. Both patients survived without complications. CONCLUSIONS:
Thyroid storm and FHF each independently carry high mortality rates, and managing patients with both conditions simultaneously is an extraordinary challenge. These cases should compel clinicians to investigate liver function in hyperthyroid patients and to be wary of its rapid decline in patients who present in thyroid storm with symptoms of liver dysfunction. Patients with rapidly progressing thyroid storm and FHF should be considered for total thyroidectomy and OLT.
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Authors | Catherine Hambleton, Joseph Buell, Bob Saggi, Luis Balart, Nathan J Shores, Emad Kandil |
Journal | The Annals of otology, rhinology, and laryngology
(Ann Otol Rhinol Laryngol)
Vol. 122
Issue 11
Pg. 679-82
(Nov 2013)
ISSN: 0003-4894 [Print] United States |
PMID | 24358627
(Publication Type: Case Reports, Journal Article, Review)
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Topics |
- Female
- Follow-Up Studies
- Humans
- Liver Failure, Acute
(etiology, surgery)
- Liver Transplantation
(methods)
- Thyroid Crisis
(complications, surgery)
- Thyroidectomy
(methods)
- Young Adult
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