Spontaneous Splenic Rupture as a Paradoxical Reaction during Treatment for Splenic Tuberculosis.

Abstract

This report describes a rare case of a patient with splenic tuberculosis (TB) who developed spontaneous splenic rupture after 10 weeks of antituberculous chemotherapy. The patient responded well to the antituberculous regimen prior to the spontaneous splenic rupture. We considered a paradoxical reaction as a cause of the splenic rupture. The patient underwent splenectomy and continuously received initial antituberculous drugs without change. To the best of our knowledge, this is the first report of spontaneous splenic rupture as a paradoxical reaction to antituberculous chemotherapy in an immunocompetent host with splenic TB.

• Authors: Hye Ju Yeo, Soo Yong Lee, Eunyoung Ahn, Eun Jung Kim, Dae Gon Rhu, Kyoung Un Choi, Seung Eun Lee, Woo Hyun Cho, Doosoo Jeon, Yun Seong Kim
• Journal: Tuberculosis and respiratory diseases (Tuberc Respir Dis (Seoul)) Vol. 75 Issue 5 Pg. 218-21 (Nov 2013) ISSN: 1738-3536 [Print] Korea (South)
• PMID: 24348671 (Publication Type: Journal Article)