HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Dry-powder inhalers in acute asthma.

Abstract
An updated literature search was performed to evaluate the efficacy of rapid-acting β2-agonists delivered via dry powder inhalers in the treatment of moderate-to-severe acute asthma. Databases were searched from 1985 up to December 2012. A total of 23 randomized, double-blind or open clinical studies in acute asthma comparing the efficacy of a dry powder inhaler with a pressurized metered-dose inhaler or a nebulizer, and performed under controlled hospital conditions, were identified. This review found that administration of β2-agonist bronchodilators via dry powder inhalers (formoterol, salbutamol, terbutaline and budesonide/formoterol) was effective during severe asthma worsening and acute asthma attacks, and was as effective as established therapies with a pressurized metered-dose inhaler with or without a spacer, or nebulization. These results ensure that patients can rely upon dry powder inhalers equally well as other inhaler devices during episodes of asthma worsening.
AuthorsOlof Selroos
JournalTherapeutic delivery (Ther Deliv) Vol. 5 Issue 1 Pg. 69-81 (Jan 2014) ISSN: 2041-5990 [Print] England
PMID24341818 (Publication Type: Journal Article, Meta-Analysis, Review)
Chemical References
  • Adrenergic beta-2 Receptor Agonists
  • Anti-Asthmatic Agents
  • Bronchodilator Agents
Topics
  • Acute Disease
  • Adrenergic beta-2 Receptor Agonists (administration & dosage, therapeutic use)
  • Animals
  • Anti-Asthmatic Agents (administration & dosage, therapeutic use)
  • Asthma (drug therapy, physiopathology)
  • Bronchodilator Agents (administration & dosage, therapeutic use)
  • Dry Powder Inhalers
  • Humans

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: