[Choice of optimal perfusion flow rate during surgical correction of combined acquired heart diseases].

Abstract

Cardiac output during the use of cardiopulmonary bypass (CPB) is defined by perfusion flow rate, which is calculated by multiplying the perfusion index (PI) on the body surface area. To date, there is no clear definition of an optimal PI and flow rate of perfusion. 60 patients operated with CPB were enrolled in the prospective study to determine the relations between different modes of perfusion and oxygen transport during surgical correction of combined valvular heart disease. Calculation of the CPB flow rate was based on PI 2.5 and 3.0 l/min/m2. Results of the study demonstrate that perfusion based on PI 2.5 l/min/m2 provides more stable oxygen transport parameters and reduces the time of ICU stay in comparison with the flow rate based on PI 3.0 l/min/m2.

• Authors: A I Len'kin, V I Zakharov, A A Smetkin, P I Len'kin, M Iu Kirov
• Journal: Anesteziologiia i reanimatologiia (Anesteziol Reanimatol) 2013 May-Jun Issue 3 Pg. 4-8 ISSN: 0201-7563 [Print] Russia (Federation)
• PMID: 24340987 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Oxygen

Topics

• Blood Flow Velocity (physiology)
• Cardiopulmonary Bypass (methods)
• Cerebrovascular Circulation (physiology)
• Data Interpretation, Statistical
• Heart Diseases (etiology, surgery)
• Humans
• Middle Aged
• Monitoring, Intraoperative (methods)
• Oxygen (blood)
• Prospective Studies
• Pulsatile Flow
• Regional Blood Flow (physiology)
• Treatment Outcome