Abstract | BACKGROUND: There are few reports regarding differences in reactivity to the major egg allergens according to children's age, although component-resolved diagnosis is gradually being used. OBJECTIVE: To investigate differences in reactivity to major egg allergens among various age groups of children with egg allergy. METHODS: Twenty-seven patients diagnosed with egg allergy were included. Egg allergy was defined as a convincing history of reproducible symptoms within 2 hours of egg consumption and an egg white-specific IgE level of at least 0.35 kUA/L. Patients were divided into 3 age groups: younger than 12 months (group A, 7 subjects), 12 to 23 months (group B, 8 subjects), and at least 24 months (group C, 12 subjects). Immunoblotting and enzyme-linked immunosorbent assay investigated IgE reactivity toward ovalbumin, ovomucoid, and ovotransferrin in eggs. RESULTS: CONCLUSION:
IgE reactivity to egg allergens differs according to children's ages.
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Authors | Jihyun Kim, Jeongok Lee, Mi-Ran Park, Youngshin Han, Meeyong Shin, Kangmo Ahn |
Journal | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
(Ann Allergy Asthma Immunol)
Vol. 112
Issue 1
Pg. 53-7
(Jan 2014)
ISSN: 1534-4436 [Electronic] United States |
PMID | 24331394
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2014 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved. |
Chemical References |
- Allergens
- Conalbumin
- Ovomucin
- Immunoglobulin E
- Ovalbumin
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Topics |
- Allergens
(immunology)
- Child
- Child, Preschool
- Conalbumin
(immunology)
- Egg Hypersensitivity
(diagnosis)
- Eggs
(adverse effects)
- Female
- Humans
- Immunoglobulin E
(blood, immunology)
- Infant
- Male
- Ovalbumin
(immunology)
- Ovomucin
(immunology)
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