Abstract | BACKGROUND: OBJECTIVE: Compare the performance and reliability ofleukocyte esterase dipstick urinalysis with microscopic examination for detection of clinically suspected UTI. MATERIAL AND METHOD: A retrospective descriptive study was conducted on 109 patients who visited the outpatient clinic with a clinical suspicion of UTI between November 2010 and July 2011. The subjects consisted ofpatients from the age of 15 years and over regardless of gender A dipstick test (Combur-Test Mstrip, Roche) was used. All dipstick-positive samples were processed to microscopic examination and urine culture was used as gold standard. Sensitivity, specificity, and predictive values were analyzed for the dipstick test ( leukocyte esterase) as compared to microscopic examination. Statistical analysis was performed by using the t-test. RESULTS: The sensitivity of leukocyte esterase test and the combined leukocyte esterase and nitrite test were 63.6% and 66.7%, respectively. The presence of pyuria demonstrated the highest sensitivity (95.6%) and specificity (60.9%) for positive urine culture compared to the dipstick test. Statistical analysis revealed a significant correlation between the dipstick test ( leukocyte esterase) and microscopic examination (p< 0. 001). CONCLUSION:
Pyuria can be used to detect UTI instead of urine culture due to its significant incidence. In the present study, the presence of pyuria had a higher specificity (60.9%) compared to the dipstick test (44.2%). However the significantly positive dipstick and pyuria results make the combined test more useful than the single test, and there is a statistically significant correlation between the dipstick test ( leukocyte esterase) and the microscopic examination (p< 0. 001). Therefore, the dipstick test ( leukocyte esterase) can be used as a diagnostic tool in detecting UTI cases.
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Authors | Sirirat Laosu-angkoon |
Journal | Journal of the Medical Association of Thailand = Chotmaihet thangphaet
(J Med Assoc Thai)
Vol. 96
Issue 7
Pg. 849-53
(Jul 2013)
ISSN: 0125-2208 [Print] Thailand |
PMID | 24319857
(Publication Type: Journal Article)
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Chemical References |
- Reagent Strips
- leukocyte esterase
- Carboxylic Ester Hydrolases
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Topics |
- Adolescent
- Adult
- Ambulatory Care
- Carboxylic Ester Hydrolases
(urine)
- Female
- Humans
- Male
- Reagent Strips
- Reproducibility of Results
- Retrospective Studies
- Sensitivity and Specificity
- Thailand
- Urinalysis
- Urinary Tract Infections
(diagnosis, metabolism)
- Young Adult
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