Abstract | BACKGROUND AND PURPOSE: METHODS: CCH patients who had a unilateral GONB and were referred to the National Hospital for Neurology and Neurosurgery were studied prospectively. Headache characteristics were collected using headache diaries. Responders were considered to be patients with a complete or partial response lasting at least 7 days. In a subgroup of responders the outcomes of serial GONB performed at 3-monthly intervals were also analysed. RESULTS: Eighty-three CCH patients were studied. After the first GONB, a positive response was observed in 47 (57%) patients: 35 (42%) were rendered pain free, 12 (15%) had a partial benefit and one patient obtained <50% improvement. The duration of a positive response lasted a median of 21 days (range 7-504 days). There was a transient worsening of condition in 6% of patients. The overall rate and average duration of response remained consistent after the second [n = 37; 31 responders (84%); median duration 21 days], third [n = 28; 20 responders (71%); median duration 25 days] and fourth [n = 14; 10 responders (71%); median duration 23 days] injections. CONCLUSION: GONB seems to be an efficacious treatment with reproducible effects in CCH patients. Performed three monthly, GONB may have a useful role in the management of CCH.
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Authors | G Lambru, N Abu Bakar, L Stahlhut, S McCulloch, S Miller, P Shanahan, M S Matharu |
Journal | European journal of neurology
(Eur J Neurol)
Vol. 21
Issue 2
Pg. 338-43
(Feb 2014)
ISSN: 1468-1331 [Electronic] England |
PMID | 24313966
(Publication Type: Journal Article, Observational Study, Research Support, Non-U.S. Gov't)
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Copyright | © 2013 The Author(s) European Journal of Neurology © 2013 EFNS. |
Chemical References |
- Analgesics
- Lidocaine
- Methylprednisolone
|
Topics |
- Adult
- Aged
- Analgesics
(therapeutic use)
- Cluster Headache
(drug therapy)
- Drug Therapy, Combination
- Female
- Humans
- Lidocaine
(therapeutic use)
- Male
- Methylprednisolone
(therapeutic use)
- Middle Aged
- Nerve Block
(methods)
- Prospective Studies
- Treatment Outcome
- Young Adult
|