Abstract | OBJECT: METHODS: The authors retrospectively reviewed all cases of glomus jugulare tumors that had been treated with preoperative embolization using Onyx at their institution in the period from 2006 to 2012. Patient demographics, clinical presentation, grade and amount of Onyx used, degree of angiographic devascularization, and procedural complications were recorded. RESULTS: Over a 6-year period, 11 patients with glomus jugulare tumors underwent preoperative embolization with Onyx. All embolization procedures were completed in one session. The overall mean percent of tumor devascularization was 90.7%. No evidence of nontarget embolization was seen on postembolization angiograms. There were 2 cases (18%) of permanent cranial neuropathy attributed to the embolization procedures (facial nerve paralysis and lower cranial nerve dysfunction). CONCLUSION: Embolizing glomus jugulare tumors with Onyx can produce a dramatic reduction in tumor vascularity. However, the intimate anatomical relationship and overlapping blood supply between these tumors and cranial nerves may contribute to a high incidence of cranial neuropathy following Onyx embolization.
|
Authors | Brandon G Gaynor, Mohamed Samy Elhammady, Daniel Jethanamest, Simon I Angeli, Mohammad A Aziz-Sultan |
Journal | Journal of neurosurgery
(J Neurosurg)
Vol. 120
Issue 2
Pg. 377-81
(Feb 2014)
ISSN: 1933-0693 [Electronic] United States |
PMID | 24313612
(Publication Type: Case Reports, Journal Article)
|
Chemical References |
- Onyx copolymer
- Polyvinyls
- Dimethyl Sulfoxide
|
Topics |
- Adult
- Aged
- Brain Neoplasms
(blood supply, surgery)
- Cerebral Angiography
- Cerebral Revascularization
- Cranial Nerve Diseases
(epidemiology, etiology)
- Dimethyl Sulfoxide
(therapeutic use)
- Embolization, Therapeutic
(adverse effects)
- Female
- Glomus Jugulare Tumor
(blood supply, surgery)
- Humans
- Incidence
- Middle Aged
- Neurosurgical Procedures
- Paralysis
(etiology)
- Polyvinyls
(therapeutic use)
- Regional Blood Flow
- Retrospective Studies
- Tinnitus
(etiology)
|