Efficacy of 5-Aminolevulinic Acid Photodynamic Therapy in treatment of nasal inverted papilloma.

Abstract

OBJECTIVE:

Evaluate the efficacy of 5-Aminolevulinic Acid Photodynamic Therapy (PDT) in medical treatment of nasal inverted papilloma (NIP).

METHODS:

Three patients with nasal inverted papilloma were treated with 5-Aminolevulinic Acid Photodynamic Therapy at our department from April to September 2012. The efficacy and adverse effects of 5-Aminolevulinic Acid Photodynamic Therapy were evaluated during 6-8 months of follow-up medical examination.

RESULTS:

After treated with 5-Aminolevulinic Acid Photodynamic Therapy, the nasal inverted papillomas were removed. No recurrence was found during the 6-8 months of follow-up medical examination. The major adverse effects were mild erosion, pain, and exudation.

CONCLUSION:

5-Aminolevulinic Acid Photodynamic Therapy appears to be an effective treatment of nasal inverted papilloma. It can clear the papilloma lesions and is well tolerated by the patients.

• Authors: Yunjie Zhang, Yuguang Yang, Xianbiao Zou
• Journal: Photodiagnosis and photodynamic therapy (Photodiagnosis Photodyn Ther) Vol. 10 Issue 4 Pg. 549-51 (Dec 2013) ISSN: 1873-1597 [Electronic] Netherlands
• PMID: 24284110 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2013 Elsevier B.V. All rights reserved.

Chemical References

• Photosensitizing Agents
• Aminolevulinic Acid

Topics

• Administration, Topical
• Aminolevulinic Acid (administration & dosage)
• Humans
• Male
• Middle Aged
• Nose Neoplasms (drug therapy, pathology)
• Papilloma, Inverted (drug therapy, pathology)
• Photochemotherapy (methods)
• Photosensitizing Agents (administration & dosage)
• Treatment Outcome