Abstract | BACKGROUND: METHODS: This study analyzed 65 children between the ages of 2 and 14 with iron deficiency anemia (39 male and 26 female). The diagnosis criteria of IDA involved hemoglobin values below 11 g/dL, hematocrit values below 33%, erythrocyte counts below 3.7 x 10(12)/L, MCV values below 70 fL. Mean corpuscular hemoglobin (MCH) values below 27 pg, and ferritin levels below 12 ng/mL. Children without bleeding symptoms with blood hemoglobin values > 11g/dL and hematocrit values above 33%, defined in our previous study, were enrolled as the control group for the PFA-100 closure time. The ranges for prolonged C/EPI and C/ ADP closure times in our center were > 160 seconds and > 110 seconds, respectively. RESULTS: There was no significant correlation between hemoglobin values and C/EPI nor with C/ ADP values. CONCLUSIONS: This study found that low hemoglobin values do not play a role in obtaining C/EPI values above 160 seconds and C/ ADP values above 110 seconds. We concluded that, patients with low hemoglobin values have no effect on the results of PFA-100, which is the screening test used to diagnose specific disorders such as von Willebrand disease or platelet secretion disorders.
|
Authors | Mehmet Akin |
Journal | Clinical laboratory
(Clin Lab)
Vol. 59
Issue 9-10
Pg. 1175-7
( 2013)
ISSN: 1433-6510 [Print] Germany |
PMID | 24273944
(Publication Type: Journal Article)
|
Chemical References |
|
Topics |
- Adolescent
- Anemia, Iron-Deficiency
(blood, physiopathology)
- Child
- Child, Preschool
- Erythrocyte Count
- Female
- Ferritins
(blood)
- Hematocrit
- Hemoglobins
(analysis)
- Hemostasis
- Humans
- Male
|