Peanut agglutinin binding as a histochemical tool for diagnosis of eosinophilic granuloma.

Abstract

Histochemical detection of peanut agglutinin binding performed on tissue sections in 11 cases of eosinophilic granuloma of bone revealed simultaneous appearance of the reaction product both at the cell surface and within the cytoplasm (in the Golgi area) of a vast majority of Langerhans' cells. Based on this unique characteristic of Langerhans' cells, peanut agglutinin binding assay may represent a simple and inexpensive tool for morphologic differentiation of eosinophilic granuloma or other types of histiocytosis X from other monocytic and histiocytic lesions in equivocal cases.

• Authors: I Hajdu, W Zhang, G B Gordon
• Journal: Archives of pathology & laboratory medicine (Arch Pathol Lab Med) Vol. 110 Issue 8 Pg. 719-21 (Aug 1986) ISSN: 0003-9985 [Print] United States
• PMID: 2425777 (Publication Type: Journal Article)

Chemical References

• Lectins
• Peanut Agglutinin

Topics

• Adolescent
• Adult
• Child
• Child, Preschool
• Eosinophilic Granuloma (diagnosis, metabolism, pathology)
• Female
• Golgi Apparatus (metabolism)
• Humans
• Infant
• Langerhans Cells (metabolism, pathology)
• Lectins (metabolism)
• Male
• Middle Aged
• Peanut Agglutinin
• Staining and Labeling