Objective. Comparing the effectiveness of
vitamin B6 (40 mg twice daily) and ginger (250 mg four times daily) in treatment of pregnancy
nausea. Methods. In a clinical trial in health centers of Qazvin University of Medical Sciences from November 2010 to February 2011 on pregnant mothers, the effects of
vitamin B6 (40 mg twice daily) and ginger (250 mg four times daily) were evaluated in treatment of pregnancy
nausea. Results. In both groups, treatments with
vitamin B6 or ginger led to significant reduction in MPUQE score. Scores of symptoms at the day before treatment in
vitamin B6 and ginger groups were 9.35 ± 1.97 and 9.80 ± 2.03, respectively, and reduced to 5.98 ± 1.45 and 6.28 ± 1.63, respectively, in the fourth day of treatment; however, mean changes in the two groups were not significantly different. Mean changes of MPUQE score in ginger and
vitamin B6 groups were 8.32 ± 2.19 and 7.77 ± 1.80, respectively, showing no significant difference (P = 0.172). Conclusion.
Vomiting was more reduced in
vitamin B6 group; however, this reduction was not statistically significant. There was no significant difference between the two groups in
nausea occurrences and their duration. No side effect was observed in either group.