Syndrome of inappropriate antidiuretic hormone secretion associated with olfactory neuroblastoma.

Abstract

This study reports a patient having olfactory neuroblastoma complicated by syndrome of inappropriate antidiuretic hormone secretion. Olfactory neuroblastoma is a rare tumor that begins in the olfactory membrane. Only 10 cases have been reported previously. Because of having nonspecific symptoms, most patients manifest at an advanced stage at the time of diagnosis. Olfactory neuroblastoma may show local invasion and/or distant metastasis. We demonstrated preoperatively clinical and biochemical parameters consistent with antidiuretic hormone syndrome turned to normal ranges after the treatment. Surgery, chemotherapy, and radiotherapy are the choices of treatment; among these, surgery is an indispensible treatment.

• Authors: Ali Cemal Yumusakhuylu, Adem Binnetoglu, Muhammet Fatih Topuz, Emine Baş Bozkurtlar, Tekin Baglam, Murat Sari
• Journal: The Journal of craniofacial surgery (J Craniofac Surg) Vol. 24 Issue 6 Pg. 2189-93 (Nov 2013) ISSN: 1536-3732 [Electronic] United States
• PMID: 24220439 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Esthesioneuroblastoma, Olfactory (complications)
• Humans
• Inappropriate ADH Syndrome (complications)
• Male
• Nasal Cavity
• Nose Neoplasms (complications)