[Vitamin D and the skin].

Abstract

Vitamin D is well known for its beneficial effects on phosphocalcic homeostasis. The discovery of the role of vitamin D in cancers, infections, cardiovascular or autoimmune pathologies have promoted interest for this molecule. Skin and vitamin D are closely related. The skin is not only the site of vitamin D synthesis, but also a target organ as calcitriol plays an important hormonal and regulatory role, acting on cell proliferation, differentiation and immunomodulation. Furthermore, vitamin D influences the incidence and therapeutic response of certain dermatoses. In addition, many medical situations, mainly dermatological, require strict photoprotection and may therefore indirectly be responsible for a vitamin D deficiency in patients. The current role of vitamin D in skin cancers, inflammatory and autoimmune skin diseases is summarized.

• Authors: F Libon, E Cavalier, A F Nikkels
• Journal: Revue medicale de Liege (Rev Med Liege) Vol. 68 Issue 9 Pg. 458-64 (Sep 2013) ISSN: 0370-629X [Print] Belgium
• Vernacular Title: La vitamine d et la peau.
• PMID: 24180201 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Vitamin D

Topics

• Carcinoma, Basal Cell (complications, epidemiology, etiology, therapy)
• Humans
• Melanoma (complications, epidemiology, etiology, therapy)
• Skin (metabolism, pathology)
• Skin Neoplasms (complications, epidemiology, etiology, therapy)
• Skin Physiological Phenomena
• Vitamin D (metabolism, physiology)
• Vitamin D Deficiency (complications, epidemiology, metabolism, therapy)