Abstract |
Sublingual immunotherapy (SLIT) is increasingly investigated and utilized for the treatment of food and pollen allergies. Previous case reports suggested that eosinophilic esophagitis (EoE) might develop as a long-term complication in children after completion of oral immunotherapy. Here, we describe a 44-year-old female with a medical history of pollinosis who for the first time in her life developed complete manifestation of EoE (peak eosinophils 164/high power field) 4 weeks after initiation of SLIT using specific soluble allergens (hazelnut, birch, alder) according to previous specific serum IgE testing. After discontinuation of SLIT, EoE resolved completely within 4 weeks without any other medical intervention. During a follow-up of 12 months the patient remained free of any esophageal symptoms. This is the first case report demonstrating a close and therefore likely causative association between pollen SLIT and EoE in an adult patient.
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Authors | Stephan Miehlke, Oral Alpan, Sören Schröder, Alex Straumann |
Journal | Case reports in gastroenterology
(Case Rep Gastroenterol)
Vol. 7
Issue 3
Pg. 363-8
( 2013)
ISSN: 1662-0631 [Print] Switzerland |
PMID | 24163646
(Publication Type: Case Reports)
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