Subcutaneous infusions of apomorphine: a reappraisal of its therapeutic efficacy in advanced Parkinson's disease.

Abstract

Subcutaneous infusion of apomorphine is a useful treatment for motor and nonmotor complications in Parkinson's disease patients and improves the patient's quality of life. An adequate selection of suitable candidates is crucial for obtaining the best results with this therapy. Parkinsonian patients with severe biphasic dyskinesias, demented or having experienced serious neuropsychiatric side effects with other dopamine agonists should not be offered this treatment. The therapeutic effect of continuous apomorphine infusion is reviewed and practical recommendations on its use are provided.

• Authors: Francisco Grandas
• Journal: Expert review of neurotherapeutics (Expert Rev Neurother) Vol. 13 Issue 12 Pg. 1343-53 (Dec 2013) ISSN: 1744-8360 [Electronic] England
• PMID: 24160681 (Publication Type: Journal Article, Review)

Chemical References

• Dopamine Agonists
• Apomorphine

Topics

• Animals
• Apomorphine (administration & dosage, therapeutic use)
• Dopamine Agonists (administration & dosage, therapeutic use)
• Humans
• Infusions, Subcutaneous (methods)
• Parkinson Disease (drug therapy)
• Quality of Life
• Treatment Outcome