Short- and long-term results of lateral pancreaticojejunostomy for chronic pancreatitis: a retrospective Japanese single-center study.

Abstract

BACKGROUND:

The study aim was to determine the short- and long-term results of lateral pancreaticojejunostomy for chronic pancreatitis at a single center in Japan.

METHODS:

The records of 64 consecutive patients were retrospectively reviewed. All patients underwent surgery at Hiroshima University Hospital between December 1996 and April 2013. Long-term follow-up was performed in 58 patients (91%) for a median period of 34 months.

RESULTS:

The 53 men (83%) and 11 women (17%) had a mean age of 55 years. The etiology of pancreatitis was chronic alcohol abuse in 44 patients (69%). The major indication for surgery was acute pancreatitis exacerbation (80%). There was no postoperative mortality. Postoperative morbidity occurred in 21 patients (33%), with severe complications requiring non-surgical intervention in four (6%). The percentage of pain-free patients after surgery was 91%, and further acute exacerbation was prevented in 95%. Four patients (7%) required subsequent surgery for pancreatitis-related complications. Of the patients that completed follow-up, 33 (57%) had diabetes mellitus, including 11 patients (19%) with new-onset diabetes; 30 patients (56%) developed pancreatic exocrine insufficiency.

CONCLUSIONS:

Full-length lateral pancreaticojejunostomy is safe, feasible, and effective for managing chronic pancreatitis. The technique prevents further exacerbations and maintains appropriate pancreatic endocrine and exocrine function.

• Authors: Takeshi Sudo, Yoshiaki Murakami, Kenichiro Uemura, Yasushi Hashimoto, Naru Kondo, Naoya Nakagawa, Taijiro Sueda
• Journal: Journal of hepato-biliary-pancreatic sciences (J Hepatobiliary Pancreat Sci) Vol. 21 Issue 6 Pg. 426-32 (Jun 2014) ISSN: 1868-6982 [Electronic] Japan
• PMID: 24155150 (Publication Type: Comparative Study, Evaluation Study, Journal Article)
• Copyright: © 2013 Japanese Society of Hepato-Biliary-Pancreatic Surgery.

Topics

• Adult
• Aged
• Aged, 80 and over
• Cohort Studies
• Female
• Follow-Up Studies
• Hospitals, University
• Humans
• Japan
• Length of Stay
• Male
• Middle Aged
• Operative Time
• Pancreaticojejunostomy (adverse effects, methods)
• Pancreatitis, Chronic (diagnosis, surgery)
• Postoperative Complications (physiopathology, therapy)
• Retrospective Studies
• Time Factors
• Treatment Outcome
• Young Adult