The Women's Health Initiative Randomized Controlled Dietary Modification Trial: an inconvenient finding and the diet-heart hypothesis.

Abstract

One goal of the US$700 million Women's Health Initiative Randomized Controlled Dietary Modification Trial was to determine whether post-menopausal women who adopted what was regarded as a 'heart healthy' low-fat diet, high in vegetables, fruits and grains, reduced their risk of developing cardiovascular disease. The trial substantially favoured the outcome in the intervention group, who also received an intensive nutritional and behaviour education programme not offered to the control group. These studies neatly disprove the diet-heart hypothesis since adoption of 'heart healthy' eating not only failed to influence future cardiac events in the healthy but it increased such events in the unhealthy and worsened diabetic control in those with type 2 diabetes mellitus. 

• Authors: Timothy David Noakes
• Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde (S Afr Med J) Vol. 103 Issue 11 Pg. 824-5 (Sep 30 2013) ISSN: 0256-9574 [Print] South Africa
• PMID: 24148164 (Publication Type: Journal Article)

Topics

• Aged
• Cardiovascular Diseases (prevention & control)
• Diabetes Mellitus (diet therapy, epidemiology)
• Diet, Fat-Restricted (adverse effects, methods)
• Feeding Behavior
• Female
• Humans
• Middle Aged
• Postmenopause
• Randomized Controlled Trials as Topic
• Risk Factors
• United States (epidemiology)
• Women's Health