Superior versus inferior conjunctival autografts combined with fibrin glue in the management of primary pterygia.

To compare the outcomes of superior versus inferior conjunctival autograft (CAU) in the prevention of recurrence after performing a pterygium surgery in patients with primary pterygia.
This was a prospective randomized study of 60 eyes of 60 patients with primary pterygium. All the eyes underwent pterygium excision and were assigned randomly to receive either superior (30 eyes) or inferior (30 eyes) CAU. All grafts were attached with fibrin glue. The patients were followed up on postoperative day 1, day 7, 1 month, 3 months, and 6 months.
Outcome measures included rate of recurrence, mean surgical time, visual analog scale pain score, and amount of pain medication required in the first postoperative week. The mean surgical time, visual analog scale pain score, and amount of pain medication required in both groups were not statistically different. A follow-up of at least 6 months (mean 5.5 ± 1.1 months) was achieved in 49 eyes of 49 patients (24 eyes in the superior CAU group and 25 eyes in the inferior CAU group). One eye in the superior CAU group (4.2%) and 1 eye in the inferior CAU group (4.0%) developed pterygium recurrence. There was no statistically significant difference in the recurrence rates between the 2 groups. In the inferior CAU group, mild localized donor site scarring was noted in 2 patients (8.3%).
Pterygium excision with superior or inferior CAU secured with fibrin glue is safe and effective. There was no significant difference in surgical time, pain, and recurrence rates of pterygium after excision with superior or inferior CAU.
AuthorsSonia N Yeung, Alejandro Lichtinger, Peter Kim, Uri Elbaz, Judy Y F Ku, Maoz D Amiran, Nathan Gorfinkle, Rachel Wolff, Allan R Slomovic
JournalCornea (Cornea) Vol. 32 Issue 12 Pg. 1582-6 (Dec 2013) ISSN: 1536-4798 [Electronic] United States
PMID24145626 (Publication Type: Journal Article, Randomized Controlled Trial)
Chemical References
  • Analgesics, Non-Narcotic
  • Fibrin Tissue Adhesive
  • Tissue Adhesives
  • Adult
  • Aged
  • Analgesics, Non-Narcotic (administration & dosage)
  • Conjunctiva (transplantation)
  • Female
  • Fibrin Tissue Adhesive (therapeutic use)
  • Humans
  • Male
  • Middle Aged
  • Ophthalmologic Surgical Procedures (methods)
  • Pain Measurement
  • Prospective Studies
  • Pterygium (prevention & control, surgery)
  • Secondary Prevention
  • Tissue Adhesives (therapeutic use)
  • Transplantation, Autologous

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