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Adrenal ganglioneuroma in a patient with polycystic ovarian disease (PCOD): a rare association.

Abstract
Adrenal ganglioneuromas are rare, benign incidentalomas of a neural crest origin. A majority of these tumours are clinically silent and discovered on imaging for unrelated reasons. Polycystic ovarian disease (PCOD) is an endocrine disorder characterised by bilateral polycystic ovaries, anovulation leading to infertility, irregular menstrual cycles and features of androgen hormone excess. Herein we report a rare case of adrenal ganglioneuroma in a 14-year-old girl with PCOD. She was referred to us by the gynaecologist after incidental detection of adrenal mass on ultrasonography. Except for raised 24 h urinary metanephrines, rest of the hormones measured were in normal range. Transperitoneal adrenalectomy was performed and histopathology was suggestive of ganglioneuroma. Postoperative recovery was excellent and she is doing well. To our knowledge it is the first such type of case to be reported.
AuthorsArvind Kumar, Vishwajeet Singh, Satyanarayan Sankhwar, Suresh Babu
JournalBMJ case reports (BMJ Case Rep) Vol. 2013 (Oct 21 2013) ISSN: 1757-790X [Electronic] England
PMID24145507 (Publication Type: Case Reports, Journal Article)
Topics
  • Adolescent
  • Adrenal Gland Neoplasms (complications, diagnosis, surgery)
  • Diagnosis, Differential
  • Female
  • Ganglioneuroma (complications, diagnosis, surgery)
  • Humans
  • Polycystic Ovary Syndrome (complications)
  • Tomography, X-Ray Computed

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