Adherence ability of Staphylococcus epidermidis on prosthetic biomaterials: an in vitro study.

Abstract

Bacterial adhesion to the surface of biomaterials is an essential step in the pathogenesis of implant-related infections. In this in vitro research, we evaluated the ability of Staphylococcus epidermidis to adhere to the surface of solid biomaterials, including oxidized zirconium-niobium alloy (Oxinium), cobalt-chromium-molybdenum alloy, titanium alloy, commercially pure titanium, and stainless steel, and performed a biomaterial-to-biomaterial comparison. The test specimens were physically analyzed to quantitatively determine the viable adherent density of the S. epidermidis strain RP62A (American Type Culture Collection [ATCC] 35984). Field emission scanning electron microscope and laser microscope examination revealed a featureless, smooth surface in all specimens (average roughness <10 nm). The amounts of S. epidermidis that adhered to the biomaterial were significantly lower for Oxinium and the cobalt-chromium-molybdenum alloy than for commercially pure titanium. These results suggest that Oxinium and cobalt-chromium-molybdenum alloy are less susceptible to bacterial adherence and are less inclined to infection than other materials of a similar degree of smoothness.

• Authors: Takayuki Shida, Hironobu Koseki, Itaru Yoda, Hidehiko Horiuchi, Hideyuki Sakoda, Makoto Osaki
• Journal: International journal of nanomedicine (Int J Nanomedicine) Vol. 8 Pg. 3955-61 ( 2013) ISSN: 1178-2013 [Electronic] New Zealand
• PMID: 24143100 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Biocompatible Materials
• Metals

Topics

• Bacterial Adhesion (drug effects, physiology)
• Biocompatible Materials (chemistry, pharmacology)
• Equipment Contamination (prevention & control)
• Materials Testing
• Metals (chemistry, pharmacology)
• Prostheses and Implants (microbiology)
• Staphylococcus epidermidis (cytology, physiology)