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25-Hydroxyvitamin D in the range of 20 to 100 ng/mL and incidence of kidney stones.

AbstractOBJECTIVES:
Increasing 25-hydroxyvitamin D serum levels can prevent a wide range of diseases. There is a concern about increasing kidney stone risk with vitamin D supplementation. We used GrassrootsHealth data to examine the relationship between vitamin D status and kidney stone incidence.
METHODS:
The study included 2012 participants followed prospectively for a median of 19 months. Thirteen individuals self-reported kidney stones during the study period. Multivariate logistic regression was applied to assess the association between vitamin D status and kidney stones.
RESULTS:
We found no statistically significant association between serum 25-hydroxyvitamin D and kidney stones (P = .42). Body mass index was significantly associated with kidney stone risk (odds ratio = 3.5; 95% confidence interval = 1.1, 11.3).
CONCLUSIONS:
We concluded that a serum 25-hydroxyvitamin D level of 20 to 100 nanograms per milliliter has no significant association with kidney stone incidence.
AuthorsStacie Nguyen, Leo Baggerly, Christine French, Robert P Heaney, Edward D Gorham, Cedric F Garland
JournalAmerican journal of public health (Am J Public Health) Vol. 104 Issue 9 Pg. 1783-7 (Sep 2014) ISSN: 1541-0048 [Electronic] United States
PMID24134366 (Publication Type: Journal Article)
Chemical References
  • Vitamin D
  • 25-hydroxyvitamin D
Topics
  • Adult
  • Age Factors
  • Body Mass Index
  • Dietary Supplements
  • Female
  • Humans
  • Incidence
  • Kidney Calculi (blood, epidemiology)
  • Male
  • Middle Aged
  • Risk Factors
  • Sex Factors
  • Vitamin D (analogs & derivatives, blood)

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