DELIGHT (delay of impaired glucose tolerance by a healthy lifestyle trial) - a feasibility study on implementing a program of sustainable diabetes prevention in German companies.

Abstract

BACKGROUND:

Ca. 50% of Germans develop prediabetes in their lifetime. Though diabetes type 2 has been proven preventable, no screening for prediabetes has been implemented. DELIGHT was designed to assess if screening for individuals at risk and long-standing diabetes prevention is feasible in the setting of companies within the scope of the German legal health system.

MATERIALS AND METHODS:

In 5 companies employees with a waist circumference of ≥ 94 (men) and ≥ 80 cm (women) were offered a check-up. Those with fasting plasma glucose ≥ 100 mg/dl (IFG) or ≥ 140 mg/dl 2 h after oral glucose load (IGT) were followed for 3 years with an optional moderate lifestyle program during the first year and quarterly assistance for another 2 years.

RESULTS:

In 241 of 300 participants the self-measured waist circumference was confirmed as elevated. 3% had type 2 diabetes, while 37% had IFG (isolated in 96%) or IGT, of whom 91.4% (men) and 76.1% (women) had a metabolic syndrome. Within 3 years in those who had lost ≥ 1 kg, weight was reduced by 3.9 kg, risk factors were improved, and no case of diabetes had developed, while among those with weight loss of < 1 kg or weight gain, 10% of men and 5% of women had developed diabetes type 2. Screening for prediabetes did not increase the number or costs of drug prescriptions.

CONCLUSIONS:

Companies provide a suitable setting for screening for prediabetes. Long-term diabetes prevention is successfully feasible within the narrow financial frame of a legal insurance system without rise of costs.

• Authors: B-C Zyriax, B Letsch, S Stock, E Windler
• Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association (Exp Clin Endocrinol Diabetes) Vol. 122 Issue 1 Pg. 20-6 (Jan 2014) ISSN: 1439-3646 [Electronic] Germany
• PMID: 24132568 (Publication Type: Clinical Trial, Journal Article, Multicenter Study)
• Copyright: © J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York.

Topics

• Adult
• Aged
• Aged, 80 and over
• Diabetes Mellitus, Type 2 (epidemiology, prevention & control)
• Feasibility Studies
• Female
• Germany (epidemiology)
• Glucose Intolerance (epidemiology, prevention & control)
• Health Plan Implementation
• Health Promotion (methods)
• Humans
• Life Style
• Male
• Middle Aged
• Private Sector
• Program Evaluation
• Risk Reduction Behavior
• Waist Circumference
• Weight Loss
• Weight Reduction Programs
• Young Adult