Abstract | AIM: METHODS: RESULTS: Erosive esophagitis was diagnosed in 507 of 5015 subjects who were individually age and sex matched to 507 esophagitis-free control subjects. In patients with erosive esophagitis, BMI, waist circumference, blood pressure, fasting plasma glucose, triglyceride levels, aspartate aminotransferase, alanine aminotransferase, the ratio of total cholesterol to HDL-C, and the ratio of low-density lipoprotein cholesterol to HDL-C were significantly higher and HDL-C was significantly lower compared to patients without erosive esophagitis (all P < 0.05). In a multivariate analysis, central obesity (OR = 1.38; 95%CI: 1.0-1.86), hypertension (OR = 1.35; 95%CI: 1.04-1.76), hypertriglyceridemia (OR = 1.34; 95%CI: 1.02-1.76), cardiovascular risk factors as defined by a ratio of total cholesterol to HDL-C > 5 (OR = 1.45; 95%CI: 1.06-1.97), and aspartate aminotransferase (OR = 1.59; 95%CI: 1.08-2.34) were significantly associated with erosive esophagitis. CONCLUSION:
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Authors | Song-Seng Loke, Kuender D Yang, Kuang-Den Chen, Jung-Fu Chen |
Journal | World journal of gastroenterology
(World J Gastroenterol)
Vol. 19
Issue 35
Pg. 5883-8
(Sep 21 2013)
ISSN: 2219-2840 [Electronic] United States |
PMID | 24124334
(Publication Type: Journal Article)
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Chemical References |
- Biomarkers
- Blood Glucose
- Cholesterol, HDL
- Cholesterol, LDL
- Triglycerides
- Aspartate Aminotransferases
- Alanine Transaminase
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Topics |
- Adult
- Alanine Transaminase
(blood)
- Aspartate Aminotransferases
(blood)
- Biomarkers
(blood)
- Blood Glucose
(metabolism)
- Blood Pressure
- Body Mass Index
- Case-Control Studies
- Chi-Square Distribution
- Cholesterol, HDL
(blood)
- Cholesterol, LDL
(blood)
- Cross-Sectional Studies
- Dyslipidemias
(blood, diagnosis, epidemiology)
- Endoscopy, Gastrointestinal
- Esophagitis
(diagnosis)
- Female
- Humans
- Liver Diseases
(blood, diagnosis, epidemiology)
- Liver Function Tests
- Logistic Models
- Male
- Metabolic Syndrome
(blood, diagnosis, epidemiology, physiopathology)
- Middle Aged
- Multivariate Analysis
- Odds Ratio
- Predictive Value of Tests
- Prevalence
- Risk Factors
- Taiwan
(epidemiology)
- Triglycerides
(blood)
- Waist Circumference
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