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The antiepileptic drug carbamazepine can cause adrenal insufficiency in patients under hormone replacement therapy for congenital adrenal hyperplasia.

AuthorsDamiano Gullo, Rossella Gelsomino, Ilenia Marturano, Domenico Restivo, Maria Luisa Arpi, Daniela Leonardi, Giuseppina Parrinello, Sebastiano Squatrito
JournalHormones (Athens, Greece) (Hormones (Athens)) 2013 Jul-Sep Vol. 12 Issue 3 Pg. 470-1 ISSN: 2520-8721 [Electronic] Switzerland
PMID24121390 (Publication Type: Case Reports, Letter)
Chemical References
  • Carbamazepine
  • Dexamethasone
  • Steroid 21-Hydroxylase
  • Fludrocortisone
Topics
  • Adrenal Hyperplasia, Congenital (complications, drug therapy)
  • Adrenal Insufficiency (etiology)
  • Adult
  • Carbamazepine (adverse effects)
  • Dexamethasone (therapeutic use)
  • Epilepsy (drug therapy)
  • Fludrocortisone (therapeutic use)
  • Hormone Replacement Therapy
  • Humans
  • Male
  • Steroid 21-Hydroxylase (genetics)

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