Abstract | OBJECTIVE: To explore the role of far infrared (FIR) radiation therapy for hemodialysis (HD) access maintenance after percutaneous transluminal angioplasties (PTA). METHODS: This was a prospective observational study. Eligible patients were those who received repeated PTA with the last PTA successfully performed within 1 week before the study enrollments. Consecutively enrolled patients undergoing successful HD treatments after PTA were randomly assigned to the FIR-radiated group or control group without radiation. FIR-radiated therapy meaning 40-minute radiation at the major lesion site or anastomosed site three times a week was continued until an end-point defined as dysfunction-driven re-PTA or the study end was reached. RESULTS: Of 216 participants analyzed, including 97 with arteriovenous grafts (AVG) (49 FIR-radiated participants and 48 control participants) and 119 with arteriovenous fistulas (AVF) (69 FIR-radiated participants and 50 control participants), the FIR-radiated therapy compared with free-radiated usual therapy significantly enhanced PTA-unassisted patency at 1 year in the AVG subgroup (16.3% vs. 2.1%; p < .01), but not the AVF subgroup (25.0% vs. 18.4%; p = .50), and this accounted for the overall improved patency rates (21.4% vs. 10.3%; p = .02). CONCLUSIONS: This study suggests FIR-radiated therapy improves PTA-unassisted patency in patients with AVG who have undergone previous PTA.
|
Authors | C-C Lai, H-C Fang, G-Y Mar, J-C Liou, C-J Tseng, C-P Liu |
Journal | European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
(Eur J Vasc Endovasc Surg)
Vol. 46
Issue 6
Pg. 726-32
(Dec 2013)
ISSN: 1532-2165 [Electronic] England |
PMID | 24119468
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
|
Copyright | Copyright © 2013 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved. |
Topics |
- Aged
- Angioplasty, Balloon
- Arteriovenous Fistula
(therapy)
- Arteriovenous Shunt, Surgical
- Female
- Graft Occlusion, Vascular
(therapy)
- Humans
- Infrared Rays
(therapeutic use)
- Male
- Middle Aged
- Prospective Studies
- Recurrence
- Regional Blood Flow
(radiation effects)
- Renal Dialysis
- Vascular Patency
(radiation effects)
|