HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

IL-12Rβ1 deficiency and disseminated Mycobacterium tilburgii disease.

Abstract
Mycobacterium tilburgii rarely causes disseminated disease. We describe a case of M. tilburgii infection in an otherwise healthy 33-year-old woman, who was found to carry bi-allelic mutations of the gene encoding the β1 chain of the IL-12 receptor.
AuthorsKinda Schepers, Liliane Schandené, Jacinta Bustamante, Jean-Paul Van Vooren, Maylis de Suremain, Jean-Laurent Casanova, Jean Cyr Yombi, Frédérique Jacobs, Françoise Mascart, Jean-Christophe Goffard
JournalJournal of clinical immunology (J Clin Immunol) Vol. 33 Issue 8 Pg. 1285-8 (Nov 2013) ISSN: 1573-2592 [Electronic] Netherlands
PMID24114017 (Publication Type: Case Reports, Journal Article)
Chemical References
  • IL12RB1 protein, human
  • Receptors, Interleukin-12
Topics
  • Adult
  • Alleles
  • CD8-Positive T-Lymphocytes (immunology, microbiology, pathology)
  • Female
  • Granuloma (drug therapy, genetics, immunology)
  • Humans
  • Killer Cells, Natural (immunology, microbiology, pathology)
  • Lymph Nodes (immunology, microbiology, pathology)
  • Mutation (immunology)
  • Mycobacterium (immunology)
  • Mycobacterium Infections, Nontuberculous (drug therapy, genetics, immunology)
  • Receptors, Interleukin-12 (deficiency, genetics)
  • Recurrence

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: