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Splenic infarction after N-butyl-2-cyanoacrylate injection for gastric varices: why does it happen?

Abstract
Recent guidelines and consensus reports recommend endoscopic injection therapy with N-butyl-2-cyanoacrylate as the first-line treatment for bleeding-isolated gastric varices and gastroesophageal varices types 1 and 2. Embolization is a rare but serious complication of cyanoacrylate injection, which may be fatal in some cases. Herein, we present a patient who developed splenic infarction after N-butyl-cyanoacrylate injection for gastroesophageal varices type 2 and discuss the potential reasons and tips to prevent the occurence of embolization.
AuthorsAydin S Köksal, Ertuğrul Kayaçetin, Serkan Torun, Vedat Erkan, Riza S Ökten
JournalSurgical laparoscopy, endoscopy & percutaneous techniques (Surg Laparosc Endosc Percutan Tech) Vol. 23 Issue 5 Pg. e191-3 (Oct 2013) ISSN: 1534-4908 [Electronic] United States
PMID24105294 (Publication Type: Case Reports, Journal Article, Technical Report)
Chemical References
  • Sclerosing Solutions
  • Enbucrilate
Topics
  • Adult
  • Enbucrilate (administration & dosage, adverse effects)
  • Esophageal and Gastric Varices (therapy)
  • Female
  • Gastroscopy (methods)
  • Humans
  • Injections, Intralesional
  • Sclerosing Solutions (administration & dosage, adverse effects)
  • Splenic Infarction (chemically induced)

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