Abstract | INTRODUCTION: METHODS: A retrospective study was conducted with chart reviews from 1996 to 2011 resulted in 74 women with Factor XI level deficiency. We compared anesthetic and obstetric management in parturients with low (≤30%) level of Factor XI to those with higher levels. RESULTS: Ninety-one pregnancy outcomes were reviewed in these 74 women with Factor XI deficiency. Forty-three women had levels ≤30% in 46 labors while 31 women had levels >30% in 45 labors. Women with low levels of Factor XI were significantly more likely to receive FFP and less likely to receive neuroaxial anesthesia. There were no anesthetic complications and no difference in mode of delivery or neonatal outcomes. DISCUSSION: This study is the first step in building a national database for anesthetic cases and outcomes of parturients with Factor XI deficiency. Further efforts must be made to provide safe analgesia for these women.
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Authors | Alon Reuveni, Sharon Orbach-Zinger, Leonid A Eidelman, Yehuda Ginosar, Alexander Ioscovich |
Journal | Journal of perinatal medicine
(J Perinat Med)
Vol. 42
Issue 3
Pg. 295-300
(May 2014)
ISSN: 1619-3997 [Electronic] Germany |
PMID | 24096436
(Publication Type: Journal Article)
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Topics |
- Adult
- Anesthesia, Obstetrical
(statistics & numerical data)
- Factor XI Deficiency
- Female
- Humans
- Middle Aged
- Peripartum Period
- Pregnancy
- Pregnancy Complications, Hematologic
- Pregnancy Outcome
- Retrospective Studies
- Young Adult
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