Abstract |
Alveolar capillary dysplasia (ACD) with misalignment of pulmonary veins (MPV) is a lethal neonatal lung disease. Death from ACD/MPV is caused by hypoxia, but the role of the MPV is unknown. Using 3-dimensional reconstruction of ACD/MPV lung tissue, we report that the veins in MPV are intrapulmonary shunt vessels, and speculate that MPV contributes to the poor prognosis.
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Authors | Csaba Galambos, Sunder Sims-Lucas, Steven H Abman |
Journal | The Journal of pediatrics
(J Pediatr)
Vol. 164
Issue 1
Pg. 192-5
(Jan 2014)
ISSN: 1097-6833 [Electronic] United States |
PMID | 24079727
(Publication Type: Comparative Study, Journal Article, Research Support, N.I.H., Extramural)
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Copyright | Copyright © 2014 Mosby, Inc. All rights reserved. |
Topics |
- Cadaver
- Diagnosis, Differential
- Humans
- Imaging, Three-Dimensional
(methods)
- Immunohistochemistry
(methods)
- Infant, Newborn
- Lung
(blood supply)
- Persistent Fetal Circulation Syndrome
(diagnosis)
- Pulmonary Alveoli
(abnormalities)
- Pulmonary Veins
(pathology)
- Reproducibility of Results
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