An exceptional case of full-thickness macular hole closure in a patient with Behçet disease.

Abstract

PURPOSE:

To present a case of a full-thickness macular hole closure in a patient with Behcet uveitis.

DESIGN:

A 23-year-old-male patient with Behcet Disease had clinically inactive uveitis with topical steroids, oral azathiopurine and cyclosporine until he developed a retinal infiltrate in the left eye which evolved into a full-thickness macular hole during the follow-up.

METHODS:

Strict control of inflammation and subsequent vitrectomy was planned. Meanwhile another attack of panuveitis developed in the left eye and subcutaneous Interferon alfa-2b interferon treatment was initiated.

RESULTS:

After 2 months, the patient was clinically inactive with complete closure of the macular hole.

CONCLUSIONS:

Strict control of inflammation may result in closure of the macular hole and avoid the need for vitrectomy.

• Authors: Didar Uçar, Eray Atalay, Yilmaz Özyazgan, Ahmet Özkök, Yeliz Yıldırım
• Journal: Ocular immunology and inflammation (Ocul Immunol Inflamm) Vol. 22 Issue 1 Pg. 79-81 (Feb 2014) ISSN: 1744-5078 [Electronic] England
• PMID: 24063599 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids
• Immunosuppressive Agents
• Interferon alpha-2
• Interferon-alpha
• Recombinant Proteins
• Cyclosporine
• Azathioprine

Topics

• Administration, Oral
• Administration, Topical
• Azathioprine
• Behcet Syndrome (complications, diagnosis, drug therapy)
• Cyclosporine (therapeutic use)
• Drug Therapy, Combination
• Fluorescein Angiography
• Glucocorticoids (therapeutic use)
• Humans
• Immunosuppressive Agents (therapeutic use)
• Interferon alpha-2
• Interferon-alpha (therapeutic use)
• Male
• Panuveitis (complications, diagnosis, drug therapy)
• Recombinant Proteins (therapeutic use)
• Remission, Spontaneous
• Retinal Perforations (etiology, physiopathology)
• Tomography, Optical Coherence
• Visual Acuity (physiology)
• Young Adult