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Micropulse diode laser treatment for chronic central serous chorioretinopathy: a randomized pilot trial.

AbstractBACKGROUND AND OBJECTIVE:
To evaluate 810-nm subthreshold diode micropulse (SDM) laser in patients with chronic central serous chorioretinopathy (CSC).
PATIENTS AND METHODS:
Prospective, randomized, double-blind, sham-controlled pilot trial. Patients were randomized to SDM laser treatment (group 1) or sham procedure (group 2). Primary outcome measure was change in best corrected visual acuity (BCVA); secondary outcome was central macular thickness after 3 months. Laser treatment was performed along the detached area. At the 3-month visit, all patients were evaluated for re-treatment if they met re-treatment criteria.
RESULTS:
Fifteen patients were included in this study: five patients in the sham group and 10 in the treatment group. At 3 months, BCVA was significantly enhanced in the treatment group (P = .006) compared with the sham group (P = .498). All patients from the sham group needed treatment after 3 months. An improvement in central macular thickness and leakage on fluorescein angiography was noted in all treated patients (in both groups).
CONCLUSION:
In this limited-size, short-term exploratory study, SDM laser was effective in treating chronic CSC. There was no evidence of retinal damage induced by treatment.
AuthorsLuiz Roisman, Fernanda Pedreira Magalhães, Daniel Lavinsky, Nilva Moraes, Flávio E Hirai, José Augusto Cardillo, Michel Eid Farah
JournalOphthalmic surgery, lasers & imaging retina (Ophthalmic Surg Lasers Imaging Retina) 2013 Sep-Oct Vol. 44 Issue 5 Pg. 465-70 ISSN: 2325-8179 [Electronic] United States
PMID24044709 (Publication Type: Journal Article, Randomized Controlled Trial)
CopyrightCopyright 2013, SLACK Incorporated.
Topics
  • Adult
  • Central Serous Chorioretinopathy (surgery)
  • Chronic Disease
  • Double-Blind Method
  • Female
  • Humans
  • Laser Coagulation (methods)
  • Lasers, Semiconductor
  • Male
  • Middle Aged
  • Pilot Projects
  • Prospective Studies
  • Visual Acuity

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