Intrasinus thrombolysis by mechanical and urokinase for severe cerebral venous sinus thrombosis : a case report.

Abstract

PURPOSE:

Cerebral venous and sinus thrombosis (CVST) is a rare stroke disorder, which requires prompt recognition and appropriate intervention to prevent a devastating outcome. Intrasinus thrombolysis is an alternative and effective method to anticoagulant therapy for the treatment of CVST, but is rarely used in Taiwan.

CASE REPORT:

A 46-year-old man presented with a one-week history of intractable headache and progressive weakness of his right lower limb. Magnetic resonance venography of the brain confirmed a diagnosis of extensive venous sinus thrombosis. The patient was successfully treated by direct intrasinus thrombolysis with urokinase.

CONCLUSION:

This case highlights the benefit of early intrasinus thrombolysis for the treatment of CVST.

• Authors: Wen-Sou Lin, Hung-Wen Kao, Chun-Jen Hsueh, Chun-An Cheng
• Journal: Acta neurologica Taiwanica (Acta Neurol Taiwan) Vol. 22 Issue 3 Pg. 122-6 (Sep 2013) ISSN: 1028-768X [Print] China (Republic : 1949- )
• PMID: 24030091 (Publication Type: Case Reports, Journal Article)

Chemical References

• Fibrinolytic Agents
• Urokinase-Type Plasminogen Activator

Topics

• Brain (drug effects, pathology)
• Fibrinolytic Agents (therapeutic use)
• Humans
• Magnetic Resonance Angiography
• Male
• Middle Aged
• Sinus Thrombosis, Intracranial (diagnosis, therapy)
• Thrombolytic Therapy (methods)
• Urokinase-Type Plasminogen Activator (therapeutic use)