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Mrap2: an accessory protein linked to obesity.

Abstract
Melanocortin receptors are critical modulators of energy balance and glucose homeostasis. Companion studies published in Science (Asai et al., 2013; Sebag et al., 2013) establish a role for melanocortin receptor accessory protein 2 (Mrap2) in regulating melanocortin receptor activity and in the development of obesity in zebrafish, rodents, and humans.
AuthorsTiemin Liu, Joel K Elmquist, Kevin W Williams
JournalCell metabolism (Cell Metab) Vol. 18 Issue 3 Pg. 309-11 (Sep 03 2013) ISSN: 1932-7420 [Electronic] United States
PMID24011068 (Publication Type: Journal Article, Comment)
CopyrightCopyright © 2013 Elsevier Inc. All rights reserved.
Chemical References
  • Carrier Proteins
  • Receptor Activity-Modifying Proteins
  • Receptor, Melanocortin, Type 4
  • Zebrafish Proteins
Topics
  • Animals
  • Body Weight (genetics)
  • Carrier Proteins (genetics)
  • Female
  • Humans
  • Male
  • Obesity (genetics)
  • Receptor Activity-Modifying Proteins (metabolism)
  • Receptor, Melanocortin, Type 4 (metabolism)
  • Zebrafish (embryology)
  • Zebrafish Proteins (metabolism)

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