Abstract | BACKGROUND: METHODS: This study, using 2005-2011 National Surgical Quality Improvement Program data, examined patients with pancreatitis or benign neoplasms. Morbidity after TP alone was compared with that after TP + IAT. RESULTS: In 126 patients (40%) undergoing TP and 191 (60%) patients undergoing TP + IAT, the most common diagnosis was chronic pancreatitis. Benign neoplasms were present in 46 (14%) patients, six of whom underwent TP + IAT. Patients in the TP + IAT group were younger and had fewer comorbidities than those in the TP group. Despite this, major morbidity was more frequent after TP + IAT than after TP [n = 79 (41%) versus n = 36 (29%); P = 0.020]. Transfusions were more common after TP + IAT [n = 39 (20%) versus n = 9 (7%); P = 0.001], as was longer hospitalization (13 days versus 9 days; P < 0.0001). There was no difference in mortality. CONCLUSIONS: This study is the only comparative, multicentre study of TP and TP + IAT. The TP + IAT group experienced higher rates of major morbidity and transfusion, and longer hospitalizations. Better data on the longterm benefits of TP + IAT are needed. In the interim, this study should inform physicians and patients regarding the perioperative risks of TP + IAT.
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Authors | Neil H Bhayani, Laura M Enomoto, Jennifer L Miller, Gail Ortenzi, Jussuf T Kaifi, Eric T Kimchi, Kevin F Staveley-O'Carroll, Niraj J Gusani |
Journal | HPB : the official journal of the International Hepato Pancreato Biliary Association
(HPB (Oxford))
Vol. 16
Issue 6
Pg. 522-7
(Jun 2014)
ISSN: 1477-2574 [Electronic] England |
PMID | 23992021
(Publication Type: Comparative Study, Journal Article, Multicenter Study, Observational Study)
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Copyright | © 2013 International Hepato-Pancreato-Biliary Association. |
Topics |
- Adolescent
- Adult
- Aged
- Blood Transfusion
- Comorbidity
- Female
- Humans
- Islets of Langerhans Transplantation
(adverse effects, methods, mortality)
- Length of Stay
- Male
- Middle Aged
- Pancreatectomy
(adverse effects, mortality)
- Pancreatic Neoplasms
(diagnosis, mortality, surgery)
- Pancreatitis, Chronic
(diagnosis, mortality, surgery)
- Postoperative Complications
(etiology, mortality, therapy)
- Prospective Studies
- Risk Factors
- Time Factors
- Transplantation, Autologous
- Treatment Outcome
- United States
- Young Adult
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