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Rifampicin-resistant Mycobacterium leprae in an elderly leprosy patient in the people's Republic of China.

Abstract
The reported number of registered leprosy patients worldwide declined with the introduction of multidrug therapy. However, the emergence of rifampicin resistance in leprosy patients engenders difficulties for an individual patient, and its dissemination could pose a threat to leprosy control. This study reports an elderly patient who was diagnosed with rifampicin-resistant lepromatous leprosy. This case indicates that inadequate treatment and poor compliance may eventually result in rifampicin resistance in Mycobacterium leprae and clinical relapse.
AuthorsMeiwen Yu, Kan Wu, Bing Pei, Degang Yang, Qiulin Wang, Hongsheng Wang, Jianping Shen, Liangbing Yan, Guochen Zhang
JournalClinical interventions in aging (Clin Interv Aging) Vol. 8 Pg. 1097-9 ( 2013) ISSN: 1178-1998 [Electronic] New Zealand
PMID23986632 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Leprostatic Agents
  • Rifampin
Topics
  • Aged
  • Drug Resistance, Microbial (drug effects)
  • Humans
  • Leprostatic Agents (therapeutic use)
  • Leprosy, Lepromatous (drug therapy)
  • Male
  • Medication Adherence
  • Mycobacterium leprae (drug effects)
  • Rifampin (therapeutic use)
  • Taiwan

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