HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

External stabilization for severe tracheobronchomalacia using separated ring-reinforced ePTFE grafts is effective and safe on a long-term basis.

AbstractPURPOSE:
Tracheobronchomalacia is a respiratory disorder that results from abnormal cartilage development. Since 2003, we have performed external stabilization for severe tracheobronchomalacia using separated ring-reinforced expanded polytetrafluoroethylene (ePTFE) grafts. The aim of this study was to analyze the short- and long-term outcomes of our procedure.
METHODS:
We reviewed the charts of patients who underwent external tracheobronchial stabilization from January 2003 through December 2012. Separated ring-reinforced ePTFE grafts were fixed to the anterior and posterior lesions of malacia independently, with confirmation of a well-opened lumen by bronchoscopy.
RESULTS:
Five children with severe tracheobronchomalacia underwent six operations. The median follow-up period was 43 months (range 11-109 months). There was no operative mortality associated with the procedure. One patient required removal of a section of the graft owing to the development of bronchial granulation tissue at the site of fixation. All patients showed improved respiratory function, and tracheal growth was confirmed by follow-up computed tomography.
CONCLUSIONS:
External stabilization with separated ring-reinforced ePTFE grafts for severe tracheobronchomalacia is effective, less invasive than alternatives and preserves the growth potential of the affected airway segment.
AuthorsShinya Takazawa, Hiroo Uchida, Hiroshi Kawashima, Yujiro Tanaka, Takayuki Masuko, Kyoichi Deie, Yuzo Nagase, Tadashi Iwanaka
JournalPediatric surgery international (Pediatr Surg Int) Vol. 29 Issue 11 Pg. 1165-9 (Nov 2013) ISSN: 1437-9813 [Electronic] Germany
PMID23982386 (Publication Type: Journal Article)
Chemical References
  • Polytetrafluoroethylene
Topics
  • Bronchi (surgery)
  • Bronchoscopy
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Male
  • Polytetrafluoroethylene
  • Prostheses and Implants
  • Prosthesis Design
  • Plastic Surgery Procedures (methods)
  • Retrospective Studies
  • Severity of Illness Index
  • Suture Techniques
  • Time Factors
  • Tomography, X-Ray Computed
  • Trachea (surgery)
  • Tracheobronchomalacia (diagnosis, surgery)
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: