Abstract | BACKGROUND/AIMS: METHODS: This is a prospective study performed in a large urban, community hospital. Consecutive gastric bypass patients seen from February 1, 2008 to May 1, 2009 are included. Thiamine deficiency in this study included both: consistent clinical symptoms and either (1) low blood thiamine level or (2) resolution of clinical symptoms after receiving thiamine. RESULTS: Of 151 patients, 25 females and 2 males met the criteria for thiamine deficiency (prevalence of 18%). In these 27 patients, 12 had one symptom of thiamine deficiency, while 15 had symptoms consistent with multiple subtypes. Eleven patients reported constipation at 0.33-12 years (mean 4.8) after gastric bypass. Elevated serum folate levels were seen in 6 of 10 tested patients and there was an abnormal glucose- hydrogen breath test in 9 of 10 tested patients, supporting the presence of small intestinal bacterial overgrowth. Frequency of defecation improved after thiamine treatment. CONCLUSION:
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Authors | Hiral N Shah, Bikram S Bal, Frederick C Finelli, Timothy R Koch |
Journal | Digestion
(Digestion)
Vol. 88
Issue 2
Pg. 119-24
( 2013)
ISSN: 1421-9867 [Electronic] Switzerland |
PMID | 23970020
(Publication Type: Journal Article)
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Copyright | Copyright © 2013 S. Karger AG, Basel. |
Topics |
- Adult
- Aged
- Constipation
(epidemiology, etiology)
- District of Columbia
(epidemiology)
- Female
- Gastric Bypass
(adverse effects)
- Humans
- Male
- Middle Aged
- Prevalence
- Prospective Studies
- Thiamine Deficiency
(epidemiology, etiology)
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