Disseminated microsporidiosis in a renal transplant recipient: case report and review of the literature.

Abstract

Microsporidia are opportunistic pathogens that usually cause a limited disease in the gastrointestinal tract. Occasionally, they can cause disseminated disease. In solid organ transplant recipients, disseminated disease has been reported only rarely. We describe a 68-year-old woman who presented with fever, cough, and acute kidney injury 6 months after kidney transplantation. Dissemination was confirmed by identification of microsporidial spores in urine and bronchoalveolar lavage fluid. Polymerase chain reaction analysis identified the species as Encephalitozoon cuniculi.

• Authors: A Nagpal, B S Pritt, E C Lorenz, H Amer, S H Nasr, L D Cornell, S Iqbal, M P Wilhelm
• Journal: Transplant infectious disease : an official journal of the Transplantation Society (Transpl Infect Dis) Vol. 15 Issue 5 Pg. 526-32 (Oct 2013) ISSN: 1399-3062 [Electronic] Denmark
• PMID: 23947513 (Publication Type: Case Reports, Journal Article, Review)
• Copyright: © 2013 John Wiley & Sons A/S.

Topics

• Aged
• Bronchoalveolar Lavage Fluid (microbiology)
• Encephalitozoon cuniculi (genetics, isolation & purification)
• Encephalitozoonosis (complications, diagnosis, microbiology)
• Female
• Humans
• Immunocompromised Host
• Kidney (pathology)
• Kidney Transplantation (adverse effects)
• Opportunistic Infections
• Spores, Fungal
• Treatment Outcome