HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Combined spinal and general anesthesia vs general anesthesia for robotic sacrocervicopexy: a randomized controlled trial.

AbstractINTRODUCTION AND HYPOTHESIS:
Gynecologic laparoscopic surgery is frequently accompanied by early postoperative pain. This study assessed the effect of combined general and spinal anesthesia on postoperative pain score, analgesic use, and patient satisfaction following robotic surgeries.
METHODS:
This was a randomized controlled trial. Thirty-eight consecutive women who underwent robotic surgeries for pelvic organ prolapse (sacrocolpopexy with or without subtotal hysterectomy) were randomly assigned to receive general anesthesia (control group, n = 20) or combined general with spinal anesthesia (study group, n = 18). Pain scores were assessed at rest and while coughing using a visual analog scale (VAS) 0-10. Dosage of analgesic medication consumption was retrieved from patients' charts.
RESULTS:
There were no statistically significant differences between the two groups with respect to demographic data and intraoperative hemodynamic parameters. In the postanesthesia care unit (PACU) mean total IV morphine and meperidine dosages were significantly lower for the study than the control group (0.33 vs 7.59 mg, 1.39 vs 27.89 mg, respectively, P < 0.003, <0.001, respectively). In addition, a significantly lower percentage of patients belonging to the study group demanded analgesic medications while in the PACU (33 vs 53 %, P = 0.042). Pain scores in the PACU and during postoperative day 1 were significantly lower in the study group than in the control group (delta VAS 1.9 vs 3.0, P = 0.04). Satisfaction with pain treatment among both patients and nurses was significantly higher in the study group.
CONCLUSIONS:
Reported levels of pain and analgesic use during the first 24 h following robotic gynecologic surgery were significantly lower following general and spinal anesthesia compared to general anesthesia alone.
AuthorsDror Segal, Nibal Awad, Hawash Nasir, Susana Mustafa, Lior Lowenstein
JournalInternational urogynecology journal (Int Urogynecol J) Vol. 25 Issue 3 Pg. 369-74 (Mar 2014) ISSN: 1433-3023 [Electronic] England
PMID23928955 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References
  • Analgesics, Opioid
  • Anesthetics, Inhalation
  • Anesthetics, Intravenous
  • Morphine
  • Meperidine
  • Isoflurane
  • Fentanyl
  • Propofol
Topics
  • Adult
  • Aged
  • Analgesics, Opioid (administration & dosage)
  • Anesthesia, General
  • Anesthesia, Spinal
  • Anesthetics, Inhalation
  • Anesthetics, Intravenous
  • Attitude of Health Personnel
  • Female
  • Fentanyl
  • Gynecologic Surgical Procedures (adverse effects, methods)
  • Humans
  • Isoflurane
  • Laparoscopy (adverse effects, methods)
  • Meperidine (administration & dosage)
  • Middle Aged
  • Morphine (administration & dosage)
  • Pain Measurement
  • Pain, Postoperative (etiology, prevention & control)
  • Patient Satisfaction
  • Postoperative Care
  • Propofol
  • Robotics

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: