[A case of diversion colitis successfully treated with 5-aminosalicylic acid].

Abstract

An 84-year-old man was admitted to our hospital because of blood in the stool. He had previously undergone a subtotal colectomy and ileostomy with a mucous fistula of the sigmoid colon because of a large bowel hemorrhage of unknown origin. Five years later, a minor hemorrhage developed in the remnant rectum. The clinical history, colonoscopic findings, and the histology of the diverted colon specimens were suggestive of diversion colitis. Treatment was initiated with short-chain fatty acid enema, but slight blood loss through the stool continued;thus, the patient was administered 5-aminosalicylic acid (5-ASA) enema. Subsequently, his symptoms and endoscopic findings improved. 5-ASA enema appears to be both safe and effective in the treatment of diversion colitis following intestinal tract surgery.

• Authors: Yoko Kominami, Hirotoki Ohe, Reiji Higashi, Ken Hirao, Tsuneyoshi Ogawa, Masahiro Nakagawa, Yasuyuki Araki, Motowo Mizuno, Kazuaki Chayama
• Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology (Nihon Shokakibyo Gakkai Zasshi) Vol. 110 Issue 8 Pg. 1447-53 (Aug 2013) ISSN: 0446-6586 [Print] Japan
• PMID: 23912004 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Mesalamine

Topics

• Aged, 80 and over
• Colectomy
• Colitis (drug therapy, etiology)
• Enema
• Humans
• Ileostomy
• Male
• Mesalamine (administration & dosage)
• Postoperative Complications