Cogan syndrome presenting after uneventful laser in situ keratomileusis.

Abstract

We report 2 cases of Cogan syndrome that developed after uneventful laser in situ keratomileusis. In the first case, an 8-month postoperative biomicroscopy revealed bilateral interface neovascularization, white intrastromal deposits, and anterior chamber cells and flare. In the second case, white cell infiltration and neovascularization were observed in the deep corneal stroma of the patient's right eye 18 months postoperatively. Based on these observations, which are consistent with typical interstitial keratitis, and the patients' history of Meniere-like disease, such as vertigo and mild hearing loss, Cogan syndrome was diagnosed in both patients. Topical steroids were prescribed. Intensive treatments with corneal irrigation and topical steroids showed effective outcomes in both cases.

• Authors: Minoru Tomita, Ayako Chiba, Naoko Inoue, Tukezban Huseynova, Tadahiko Tsuru, George O Waring 4th
• Journal: Journal of cataract and refractive surgery (J Cataract Refract Surg) Vol. 39 Issue 8 Pg. 1260-6 (Aug 2013) ISSN: 1873-4502 [Electronic] United States
• PMID: 23889869 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2013 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

Chemical References

• Glucocorticoids
• Ophthalmic Solutions
• dexamethasone sulfate ester
• Dexamethasone

Topics

• Adult
• Cogan Syndrome (diagnosis, drug therapy, etiology)
• Corneal Neovascularization (diagnosis, drug therapy, etiology)
• Corneal Topography
• Dexamethasone (analogs & derivatives, therapeutic use)
• Female
• Glucocorticoids (therapeutic use)
• Humans
• Keratomileusis, Laser In Situ
• Lasers, Excimer
• Male
• Ophthalmic Solutions
• Postoperative Complications
• Tomography, Optical Coherence
• Tomography, X-Ray Computed
• Visual Acuity