Abstract | BACKGROUND: Early infant (1-60 days of life) male circumcision is being trialed in Africa as a human immunodeficiency virus prevention strategy. Postcircumcision bleeding is particularly concerning where most infants are breastfed, and thus these infants are at increased risk of vitamin K deficiency bleeding. CASE: During a circumcision trial, one infant bled for 90 minutes postprocedure. After discovering he had not received standard prophylactic vitamin K, we gave 2 mg phytomenadione ( vitamin K1) intramuscularly; bleeding stopped within 30 minutes. CONCLUSION:
Vitamin K's extremely rapid action is not commonly appreciated. Neonatal vitamin K has been shown to be cost-effective. To increase availability and promote awareness of its importance, especially in low-resource settings where blood products and transfusions are limited, vitamin K should be included in the World Health Organization's Model List of Essential Medicines for Children.
|
Authors | Rebeca M Plank, Tara Steinmetz, David C Sokal, Martin J Shearer, Santorino Data |
Journal | Obstetrics and gynecology
(Obstet Gynecol)
Vol. 122
Issue 2 Pt 2
Pg. 503-505
(Aug 2013)
ISSN: 1873-233X [Electronic] United States |
PMID | 23884276
(Publication Type: Case Reports, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
|
Chemical References |
|
Topics |
- Africa
- Circumcision, Male
(adverse effects)
- Hemorrhage
(drug therapy, etiology, prevention & control)
- Humans
- Infant, Newborn
- Male
- Vitamin K 1
(therapeutic use)
- Vitamin K Deficiency
(complications)
- Vitamins
(therapeutic use)
|