Dysembryoplastic neuroepithelial tumor with rapid recurrence of pilocytic astrocytoma component.

Abstract

Dysembryoplastic neuroepithelial tumor (DNT) rarely has aggressive behavior with recurrence. The authors describe a case of DNT with rapid re-growth and features of pilocytic astrocytoma. A 19-year-old girl presented with a 3-year history of complex partial seizure, which was presumably because of DNT located in the left parietal lobe. The tumor was resected, although a tiny residual lesion with cystic space enlarged with ring enhancement identified on MRI 14 days after surgery resulted in re-excision. The recurrent tumor was eventually proved to be predominantly composed of pilocytic astrocytoma. DNT is known to recur only rarely as a tumor with morphologically different components, and no cases of recurrent DNT with rapidly-growing pilocytic astrocytoma have hitherto been reported in the literature. This phenomenon may be histological "replacement" at recurrence.

• Authors: Yasuhide Takeuchi, Yoshiki Arakawa, Yoshiki Mikami, Riki Matsumoto, Susumu Miyamoto
• Journal: Brain tumor pathology (Brain Tumor Pathol) Vol. 31 Issue 2 Pg. 144-8 (Apr 2014) ISSN: 1861-387X [Electronic] Japan
• PMID: 23881357 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't, Review)

Topics

• Adult
• Astrocytoma (diagnosis, pathology, surgery)
• Brain Neoplasms (diagnosis, pathology, surgery)
• Epilepsies, Partial (etiology)
• Female
• Humans
• Magnetic Resonance Imaging
• Neoplasm Recurrence, Local
• Neoplasms, Multiple Primary
• Neoplasms, Neuroepithelial (diagnosis, pathology, surgery)
• Parietal Lobe
• Reoperation
• Young Adult