Abstract | OBJECTIVE: METHODS: A retrospective study was performed for 6 inpatients with p-ANCA associated hypertrophic pachymeningitis at our hospital from 2005 to 2012. RESULTS: There were 3 males and 3 females with an age range of 52 - 68 years. The main clinical manifestations included headache and multiple cranial neuropathies. Erythrocyte sedimentation rate, C-reactive protein, titer of myeloperoxidase (MPO)- ANCA and protein in cerebrospinal fluid were uniformly elevated in all 6 patients during active phase while cytoplasmic( c)-ANCA was all negative. Head magnetic resonance imaging (MRI) enhancement scan had a high diagnostic sensitivity. Different parts of dura were all thickened and obviously enhanced. Glucocorticoid was uniformly effective. During the follow-up period, 2 cases relapsed and received immunosuppressive agents. CONCLUSION:
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Authors | Peng Zhao, Ben-shu Zhang |
Journal | Zhonghua yi xue za zhi
(Zhonghua Yi Xue Za Zhi)
Vol. 93
Issue 11
Pg. 837-40
(Mar 19 2013)
ISSN: 0376-2491 [Print] China |
PMID | 23859390
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Antibodies, Antineutrophil Cytoplasmic
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Topics |
- Aged
- Antibodies, Antineutrophil Cytoplasmic
(blood)
- Female
- Humans
- Hypertrophy
- Male
- Meningitis
(blood, diagnosis)
- Middle Aged
- Retrospective Studies
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