Abstract | STUDY OBJECTIVES: METHODS: A total of 344 workers (age: 40.1 ± 10.5 years, male: 204, female: 140) were included in the study. The serum BDNF levels were categorized into tertiles according to sex. RESULTS: The prevalence of dyssomnia was 35.1% in males and 30.0% in females. In the females, the BDNF levels were found to be negatively associated with dyssomnia after adjusting for age, body mass index, hypertension, dyslipidemia, hyperglycemia, depression, smoking, alcohol intake, and regular exercise. Compared with the females in the high BDNF group, the multivariate odds ratio (95% CI) of dyssomnia was 2.08 (0.62-6.98) in females in the moderate BDNF group and 8.41 (2.05-27.14) in females in the low BDNF group. No such relationships were found in the males. CONCLUSIONS: The serum BDNF levels are associated with dyssomnia in Japanese female, but not male, workers.
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Authors | Reiko Nishichi, Yu Nufuji, Masakazu Washio, Shuzo Kumagai |
Journal | Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
(J Clin Sleep Med)
Vol. 9
Issue 7
Pg. 649-54
(Jul 15 2013)
ISSN: 1550-9397 [Electronic] United States |
PMID | 23853557
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Brain-Derived Neurotrophic Factor
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Topics |
- Adult
- Brain-Derived Neurotrophic Factor
(blood)
- Dyssomnias
(blood)
- Employment
- Female
- Humans
- Japan
- Male
- Odds Ratio
- Sex Factors
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